In a press release from the publisher of the journal, the study’s authors said they believe that their results contribute to an understanding of how aneurysms develop and progress, and can stimulate new treatments for patients who have or have an aneurysm or at risk of developing one. The current methods of treatment include control of blood pressure, smoking cessation, and possibly surgery to try to prevent future rupture.cerebral aneurysms occur when a blood vessel in the brain weakens and swells, it could lead to a hemorrhagic (bleeding) stroke, if the vessel bursts. These types of aneurysms are more common in women than in men, probably because less hormones after menopause, women play a role in their development, the study authors noted.
Women who had cerebral aneurysms were significantly less likely to have used oral contraceptives or hormone replacement therapy, and were also more likely to be in menopause earlier, according to the report published online May 4 in the Official neurointerventional surgery.
cerebral aneurysms are more common after 40 years and are more likely to erupt when people are in their 50s.
However, commenting on the study, the neurologist Dr. Cathy Sila says the research is flawed and its conclusions exaggerated.
Another expert called the discovery «interesting», but stressed that further study was needed.
For more information on aneurysms, visit the U.S. National Library of Medicine.
Thursday, May 5 – taking the contraceptive pill or hormone replacement therapy might protect women against cerebral aneurysms in later life, according to a new study, although a neurologist questioned the quality of research.
Since estrogen is important for the repair and maintenance of the walls of blood vessels, a decrease in hormone levels is considered the reason for the increased risk to the structure of these vessels, the study authors noted in background information on research.
In the study, Dr. Michael Chen, Rush University Medical Center and colleagues interviewed 60 women who had suffered cerebral aneurysms and questioned about their use of birth control pills and hormone replacement therapy, and compared their responses to those of a group of nearly 4,700 other women in the U.S. population.
«[It] deserves further investigation in a large group of women,» said Dr. David J. Langer, director of cerebrovascular Cushing Institutes of Neuroscience Research, part of the North Shore-Lij Health in Manhasset, NY «Undoubtedly, women maintain a high risk of cerebral aneurysms than men, and the connection to the hormonal differences between men and women may be a contributing factor in this preference, he said.
More research is more reliable, said Silas, director of the Center for cerebrovascular disease and University Hospitals Case Medical Center in Cleveland. «Doctors are much more familiar in the data, he said, adding that he hoped that the study does not convince doctors to change their prescription birth control and hormone replacement therapy.
Previous research has suggested that the use of the pill reduces the risk of hemorrhage (bleeding), stroke in adulthood. However, women who is menstruating at an early age, have no children, or both, a higher risk.
«Every time that such studies are published, one must be cautious in drawing general conclusions, but the results do not support more research in this area,» said Langer. «One question you might have is that the incidence of hypertension and smoking in this group of 60 women, and how it compares with the largest group of control?»